@Vitaliy

Your political predispositions make communication impossible.

[VK- all personal thing - to PM]

well no, they're only important to you, and few agree. In fact your political opinions are only evidence of your flaws. And because you use them as a weapon by wielding the delete button. Anyone who doesn't agree with your diatribe is berated and punished. And personally I haven't seen any evidence of your self assumed intellectual superiority. And I also like things out in the open, not manipulated by a some miniature napoleon. Anyone who doesn't should be suspect. In any other place on the internet you would be a troll.

So... I’m no moderator, but this exchange at this level has nothing to do with coronavirus thread, yes I know both of you manage big intellect and are more stubborn that and ancient Inca monolith. please guys, fighting is permitted, but this will become carnage if both of you continue at this pace. Maybe a pause?

Cheers

Chinese authorities have refused to provide experts from the World Health Organization (WHO) with raw data on early cases of coronavirus infection, which could help determine how and when the virus began to spread in the country. This is reported by The Wall Street Journal with reference to WHO representatives.

Beijing has rejected requests from experts to provide data on 174 cases of COVID-19 that were identified in Wuhan in December 2019. Instead, the Chinese authorities and scientists have shared their own research on these cases, according to WHO experts. They also presented an analysis of medical records several months before the outbreak of COVID-19, according to which no cases of coronavirus had been detected in the country before.

All sponsored by US/EU media in Mordor made half turn during last week and started carefully blaming China, but adding that "may be not" or "we need to explore further". I expect full turn to take another 1-2 weeks and after this China will be officially named world criminal, so @kurth will be more than happy.

@zcream

Issues with west economic is so severe as they couldn't not delay new huge QE any longer, and it will be nice to also kill few millions of small businesses in the process.

Blaming China is also nice thing, especially as they participated in building lab, teaching and working with it, perfectly knew that they work with similar viruses.

China is actually far behind US and EU in making such dangerous viruses as this year we got knowledge that US has special DNA/RNA printers that are able to produce viruses directly. China don't have this and still rely using methods that are 3-7 years old.

Can it be accidentally leaked virus? No, from the knowledge we have now. As binding site is too perfect, virus itself is too perfect. Accidental leaks look like previous SARS and similar viruses.

Also preparations during 2019 (even if you read PV) show that it was not accident, in 2019 began huge pressure on any anti vaccines groups in English language internet part, pressure on any conservative groups as they could resist measures that had been planned. Youtube and Google already formed organisation structures and already wrote software that they used during 2020.

Pressitutes behavior also shows vast western interests where they behaved in sync concerning travel bans (to allow enough virus in), telling that you don't need masks (same thing, to help initial spread), promotion of fake safety feeling via social distancing PR (that never helped much), all of them told that it is not China and it is 100% natural virus and now they started to turn in full sync.

@kurth

You try again to somehow ignore economic situation and fundamental interests. And also ignore all that happened during 2019 and early 2020 in informational space and that proved that US/EU/UK stand behind this. You also ignore amazing synchronization in actions during 2020 among all this countries and many of their EU colonies, even if went against any logic they acted as one.

@kurth

Your constant problem is that you try to attack opponent because you can't keep discussion level, and you can't keep it as you are lazy. I told you - read and think, drop all this lazy stuff you so like.

There’s a lot of good information out there about all this, but this new paper is a good one-stop-shop. It’s from a large multi-center team in the UK, and it concentrates on the B.1.1.7 variant. That one, the B.1.351, and the P.1 variants all have multiple mutations , with several of them in the Spike protein and indeed in its “business end”, the receptor-binding domain (RBD) that interacts with the ACE-2 protein on the surface of human cells. The N501Y mutation is common to all three of them, and that is a very strong indication that it by itself provides some fitness advantage – you have it as part of three expanding variants in completely different parts of the world, each with their own suite of other mutations.

On various mutations, check

https://blogs.sciencemag.org/pipeline/archives/2021/02/18/coronavirus-variants

After receiving the first dose of the vaccine, COVID patients produce higher levels of antibodies than those who have not yet been infected, scientists said. They admitted that for this group of people a second dose may not be needed.

Mordor progress

The first is a unique drug based on the use of microRNAs that block certain sites of the RNA virus, and those sites that are responsible for copying the virus molecule are the so-called RNA polymerase site. We named this drug Mir-19, because microRNA, first of all, is absolutely safe for humans, it does not affect the human genome, it does not affect human immunity, but at the same time highly efficiently targets the virus (in experiments on animals in Virus carriership decreases 10 thousand times), but, in addition, it prevents the most severe forms of coronavirus infection, including preventing pneumonitis, acute respiratory distress syndromes against the background of coronavirus infection.

On December 30, we received permission for clinical trials - everything was already finished, the entire preclinic. Immediately after the New Year, these clinical trials began. But taking into account the fact that this is a new molecule - it is new and patented and has no analogues - we go through the first phase especially carefully, since we need to prove safety already in humans. We will finish the first phase by mid-March and move on to working with patients, and move on to the second phase.

And the second point is the development of a new technological platform for the creation of the next generation of vaccines against COVID. If the variability of the virus is such that the accumulated mutation in the S-protein in the receptor domain will not allow antibodies to bind, we are developing a vaccine that differs in that it affects not the S-protein, but other protein components of the virus and first of all, it causes the development of not humoral immunity, that is, through the activation of antibodies, but the development of cellular immunity, cytotoxic immunity, the advantage of which is duration. If antibody immunity usually lasts for months, then cellular immunity for years, and in certain experimental studies it has been proven that this immunity is preserved up to 13-17 years.

The first formulation of this drug, a candidate drug, has now been received. We are currently preparing for clinical trials. We very much hope that by the second half of this year we will enter clinical trials.

This direction is absolutely in the trend of international interests now. The World Health Organization meeting on vaccines confirmed the trend towards the creation of next generation vaccines now, in case the variability of the virus prevents the use of antibody vaccines. Therefore, we hope that we will be fully armed.

Words about "second point" are extremely important.

First it had been openly told that is planned - changing S-protein to stop any vaccine working. so, fight will go into cellular war of weapon and defense inside cells.

Expect it all as soon as 2021.

“I started getting texts and calls from some of my colleagues saying hey, are your patients with long COVID reporting that they’re feeling better after the vaccine?” says Griffin, an infectious diseases clinician and researcher at Columbia University. When he started talking with patients, he saw that they were. “It’s not 100 percent, but it does seem like to be around a third,” he says.

New propaganda wave. Vaccines are extremely profitable and no one knows that they bring, as plan seems to be long, for 4-5 years.

@firstbase

If you go back in topic you'll find that Mordor actually threatened US that we have 99% efficient cure that is not vaccine (as far as I remember it is delivered via inhalation). Next week after this all western media suddenly started to love Sputnik V vaccine.

In short - governments now treat their people like pets, not providing simple cure, not talking about Vitamin D and HCQ and so on. They are now in phase of pets population reduction and pets instead of realizing it still mostly look at ruling class with big loving eyes.