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Coronavirus: Vaccines efficiency
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  • @mitkoo

    MICRON may have chance to become a kind of natural vaccine?

    It is clearly 100% bullshit.

  • New Twitter rules

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    Don't like some facts? Just ban anyone who mentioned them!

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  • In principle, ONS vaccine mortality surveillance reports should provide us with all the information we need to monitor these critical indicators. However, until recently, we did not see a breakdown by age in them, and given the fact that the elderly were initially vaccinated much more often than young people, this made it impossible to assess the effectiveness of vaccination.

    Now age data has begun to be added to ONS reports - there are separate groups for ages 60-69, 70-79 and 80+, but only one for 10-59.

    At first glance, mortality (for all reasons) in groups 60-69, 70-79 and 80+ decreases after vaccination, and in group 10-59 it increases, but this is only because the latter group is very large and, taking into account a different proportion vaccinated at different ages, such a rough breakdown does not allow evaluating the effectiveness.

    But at least for the elderly, do we see evidence of the effectiveness of vaccination?

    Alas, this is also in doubt, since there are fundamental inconsistencies in the data, namely:

    • in each of these age groups, we see jumps in non-covid mortality among the unvaccinated, going beyond the expected historical static intervals
    • even if these jumps took place within historical intervals, they are much higher than similar jumps among vaccinated in the same period
    • in previous years, jumps in mortality in groups 60-69, 70-79 and 80+ occurred at the same time. But in 2021, they all peaked at different times, and synchronized with the peak of vaccination programs for these ages.
    • the peaks of covid mortality among the unvaccinated do not correlate well with the peaks of infection

    There is no reliable legitimate explanation for these anomalies. But the most probable and simple ones are obvious:

    • there is a systematic violation of the mortality categories between vaccinated and unvaccinated
    • there is a delay or lack of communication about the vaccination performed, especially if it resulted in death
    • systematic underestimation of the proportion of unvaccinated
    • incorrect definition in the statistics of Covid-mortality

    Based on the validity of these assumptions, we tried to adjust the ONS data to estimate post-vaccination mortality correctly, and concluded that the short-term effect of vaccination is not a reduction in mortality, but a spike.

    https://www.researchgate.net/publication/356756711_Latest_statistics_on_England_mortality_data_suggest_systematic_mis-categorisation_of_vaccine_status_and_uncertain_effectiveness_of_Covid-19_vaccination

  • @Vitaly If omicron is less letal and much more transmissive what can we expect? Why south Africa population has high immunity despite low vaccinations? I hope for positive.

  • Most new Covid cases in Denmark occur in people who are vaccinated or boosted - and that is true for both Omicron and earlier variants. More than 76 percent of non-Omicron Covid infections in Denmark are in vaccinated people, along with about 90 percent of Omicron infections.

    Further, only 25 of the 561 people currently hospitalized in Denmark for Covid have the Omicron variant.

  • The latest study (courtesy of the UKHSA) also offered insights on the limits of vaccines and boosters when it comes to omicron, and, as one might expect given all the strain's mutations, it found that the efficacy of booster shots vs. the new variant begins to wane even more quickly than against earlier variants like delta.

    After 10 weeks of patients' last booster, immunity has already fallen 15-25%.

    The UKHSA also found that patients are between 31% and 45% less likely to attend emergency departments compared to those with delta, and 50-70% less likely to require admission to hospital.

    "Our latest analysis shows an encouraging early signal that people who contract the Omicron variant may be at a relatively lower risk of hospitalisation than those who contract other variants. However, it should be noted both that this is early data and more research is required to confirm these findings."

  • My son ( four years old ) was playing and suddenly I heard him ...Pfizermannnnn...I thought to myself what the f*... and again...Pfizermannnn... What a world are we living in???!!!...

  • Today, the U.S. Food and Drug Administration amended the emergency use authorization (EUA) for the Pfizer-BioNTech COVID-19 Vaccine to:

    • Expand the use of a single booster dose to include use in individuals 12 through 15 years of age.
    • Shorten the time between the completion of primary vaccination of the Pfizer-BioNTech COVID-19 Vaccine and a booster dose to at least five months.
    • Allow for a third primary series dose for certain immunocompromised children 5 through 11 years of age.

    As expected.

  • @Vitaliy_Kiselev

    That's disturbing. There are also rumors that the lot numbers from the Pfizer, Moderna and Johnson and Johnson vaccines vary in terms of toxicity.

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  • Steve Kirsch on the line - it is not 3 months, you need to get jab each month

    After 90 days, the vaccine they gave you is going to make you MORE likely to get infected from Omicron, not less. The longer you stay on the vaccine treadmill, the harder to get off in the future and the easier you’ll make it for the virus.

    Study shows that after three months the vaccine effectiveness of Pfizer & Moderna against Omicron is actually negative. Pfizer customers are 76.5% more likely and Moderna customers are 39.3% more likely to be infected than unvaxxed people.

    https://www.medrxiv.org/content/10.1101/2021.12.20.21267966v2

    This paper means we will need to inject people every 30 days if we want to “protect” them. If people don’t get boosted as required, they will be MORE vulnerable to Delta and Omicron than if they weren’t vaccinated. As vaccine is suppressing your immune system, probably permanently each time we are injected according to Dr. Ryan Cole.

    https://stevekirsch.substack.com/p/new-study-shows-vaccines-must-be

  • @Vitaliy_Kiselev

    That is bad news for most everyone except big pharma. One wonders if this was the plan all along.

  • Mordor lies

    The coronavirus pandemic will end when 70% of the population can be vaccinated in six months, otherwise the incidence waves can be counted indefinitely, told Alexander Gintsburg, director of the Gamaleya Research Center for Epidemiology and Microbiology.

    “If 70% of the population is vaccinated in six months, then the pandemic will end, then we will open the borders, return to our usual life.

    He noted that it is also important to undergo revaccination six months after vaccination.

    But, well, lot of EU countries crossed this number long ago, take Italy as example with 90% vaccinated - but they instead went into fascism, not normal previous life.

  • Well, even natural immunity is now declared bad

    Antibodies that appear in those who have had COVID-19 have been able to attack healthy cells of organs and tissues of the body. The dangers of antibodies were discussed by a group of researchers from the Heart Institute in Los Angeles in the Journal of Translational Medicine.

    As the scientists found, a few months after a person recovered from the coronavirus, he has an increased level of antibodies that can work incorrectly and be dangerous.

    So, in 177 medical workers who had an infection before the advent of vaccines, persistent antibodies that could cause chronic inflammation, damage to joints, skin and nervous system were detected for six months.

    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-03208-3

  • And Omicron has same quality as Delta

    Scientists at the Institute for Primate Research in Göttingen (Germany) have found that the omicron variant of the coronavirus is resistant to major antibodies. The researchers showed that the antibodies of the recovered people practically did not inhibit the omicron variant.

    http://dx.doi.org/10.1016/j.cell.2021.12.032

    It is around 99% probability that all 3 major COVID variants are lab created.

  • Strange focus on spike protein only can have simple explanation

    “Being exposed to the SARS-CoV-2 virus doesn’t always result in infection, and we’ve been keen to understand why. We found that high levels of pre-existing T cells, created by the body when infected with other human coronaviruses like the common cold, can protect against COVID-19 infection,” Dr. Rhia Kundu, the lead author, of Imperial’s National Heart & Lung Institute, said in a statement.

    Professor Ajit Lalvani, another author, said the study “provides the clearest evidence to date that T cells induced by common cold coronaviruses play a protective role against SARS-CoV-2 infection,” adding that “these T cells provide protection by attacking proteins within the virus, rather than the spike protein on its surface.”

    https://www.nature.com/articles/s41467-021-27674-x

    It seems like we are victims of special operation. Because natural immunity from Alpha variant strangely don't work for Delta variant, but vaccine do, same is true for Omicron. Yes, vaccines have lower efficiency, but they are extremely narrow and it is very improbable that virus mutations will go such abnormal way each time.

    Each of new variants appeared EXACTLY in proper time as population gained natural immunity against previous variant. Such things can't happen naturally.

    Also note that never in history virus had been able to improve 75 times in around 1-1.5 years time, almost totally change symptoms, as well as develop around 150 extremely successful changes.

    Also never before we had any air transmitted virus that had been able to spread without assist of cough process.

    First measure must be total 100% detention of all virologists, closure and, if necessary, destruction of all 100% virus related labs, including special and military, as well as seizing of all vaccine producing facilities with 100% open check available to any citizen online for each batch produced.

    Also around 40% of world supercomputers now work big part of their time on 3d protein folding tasks, including finding new folding methods of COVID spike protein. This allows to hide parts of protein such way that your antibodies don't work. Without help of this scientists governments won't be able to feed you new virus variants.

  • Pfizer CEO Albert Bourla on Monday said two doses of the company’s vaccine may not provide strong protection against infection from the Covid omicron variant, and the original shots have also lost some of their efficacy at preventing hospitalization.

    Bourla, in an interview at J.P. Morgan’s health-care conference, emphasized the importance of a third shot to boost people’s protection against omicron.

    “The two doses, they’re not enough for omicron,” Bourla said. “The third dose of the current vaccine is providing quite good protection against deaths, and decent protection against hospitalizations.”

    Even booster no longer protects you from hospitalization.

  • Israel madness

    Prime Minister Naftali Bennett made a special address to the people on the evening of January 11 in connection with the surge in the incidence of coronavirus. Bennett warned that during the current - the fifth - wave of the epidemic in the country there will be "several million infected".

    Note that almost all population have 3 shots and many already have 4!

    Bennett noted that in other countries of the world the number of infected people is estimated at many millions and even quarantine restrictions do not save.

    Bennett urged senior citizens to act with extreme caution in the coming weeks. "These will be tough weeks, but we can handle it," he said, adding that his government "has not lost control of the situation."

    According to the prime minister, his task is to maintain a functioning economy, protect vulnerable citizens and children. “I don’t want to see people fired,” he said. “It's easy to fire and close a case.

    The prime minister said that a large amount of medicine for coronavirus has been delivered to the country.

    As for the danger of "Omicron" for children, Bennett warned that this strain affects young children, although most tolerate it asymptomatically. "Many children will be in quarantine because not all are vaccinated. I urge parents to vaccinate their children," he said.

    Bennett cautioned that unvaccinated children may be severely ill, but there won't be many.

    At the same time, Bennett promised to provide each child with three free rapid antigen tests. They will arrive in the coming weeks. He also promised that the waiting lists for tests will be reduced.

    "We have difficult weeks ahead of us, but we have not lost control of the situation. Tsunami comes and goes," Bennett assured. "Everyone must take responsibility for themselves and their children. We must protect the most vulnerable."

    Bennett then answered questions from reporters. In particular, when asked whether Israel deliberately follows the path of mass infection to develop herd immunity, the prime minister replied: "We manage the epidemic better than almost anywhere in the world."

    Bennett: "I understand the frustration of the citizens. The situation will improve soon."

    Just two days ago, on January 9, the prime minister warned that "in the current wave of the epidemic, between two and four million citizens could be infected."

  • Lies and more lies

    It used to be that vaccinated people had a better chance of not getting infected than others. Now it seems that the chances are the same for those who are vaccinated and those who have been ill. Will everyone be ill with Omicron?

    In a pandemic, both before and now, the chances of getting infected in vaccinated and unvaccinated were and remain almost the same. This is one of the misunderstandings among the population: "If I have been vaccinated, then I will not get infected." No. Everyone gets infected. Vaccination only slightly reduces the chance of developing the disease. Due to the vaccine, the virus can be blocked at a very early stage, after attaching to the epithelium of the upper respiratory tract. In this case, the person will become infected, but without further severe development of the disease. The disease in this case may go in a milder form, since the immune mechanisms will quickly block the virus.

    We evaluate the epidemiological effectiveness of a vaccine by what percentage of those vaccinated will develop the disease and what percentage of those who develop the disease will have a severe form of the disease. If the vaccine protects against severe forms, then it is effective.

    Will viruses evolve in those who have not been vaccinated or have been ill for a long time, who have a low level of immunity to coronavirus?

    Everyone will evolve. But the chance of new variants appearing is much higher in people who have not been vaccinated. An unvaccinated person is, as it were, a springboard for the evolution of the virus. If a person is vaccinated, then the chance that his virus will evolve and be transmitted to someone is much lower, because he may not get sick at all and not become a source of infection.

    In a population where there are many unvaccinated people, the chances of the virus evolving are higher, it has more advantages. This explains the many variants of coronavirus, as millions of people around the world are sick at the same time. If the number of these bridgeheads is reduced through vaccination, then the risk of new variants appearing and spreading will decrease.

    The latter is a strain or not, depends on vaccination, on the availability of effective antiviral agents, on compliance with anti-epidemic measures. These factors are the main contributors to what we will see next: whether it will be a dozen more new options or whether the pandemic will end at the “omicron”.

    According to preliminary data, Omicron is neutralized by antibodies obtained from vaccination with Pfizer and Moderna drugs, 20–40 times worse than Delta. What about our vaccine?

    The "omicron" contains many mutations in the surface S-protein, on which the action of vaccines is based. Therefore, concerns about a decrease in the effectiveness of drugs arose immediately. However, as a result of research at the Center. Gamaleya, as well as in Italy on the basis of the Spallanzani Institute, it was confirmed that vaccination with the Russian "Sputnik" reliably protects against the severe course of "omicron", if after six months you undergo a booster vaccination with a one-component vaccine "Sputnik Light".

    Developers from BioNTech say that a booster vaccination will need to be done every three months due to the spread of "omicron". What are the prospects for Sputnik V in this regard? Do we also need a booster every three months or less to keep antibody levels high?

    As you understand, while this is in some sense assumptions and theories. But today we see that revaccination every six months is enough to maintain a sufficient level of immunity.

    In Russia, it is customary to measure the level of antibodies. People are wondering exactly how many antibodies can protect against infection. WHO does not provide such data. Representatives of the Center Gamalei Alexander Gunzburg and Denis Logunov said that 300 international units (BAU) are enough to protect against the delta strain. Does this antibody titer really protect against the virus?

    Indeed, opinions were voiced that if 300 and above, then with a probability of 80% you will not get infected, but here I agree with WHO, because measuring antibodies and deciding whether to be vaccinated or not, based on this, unfortunately, has no a scientific basis. The most correct thing is to simply get vaccinated in accordance with the recommendations given now by the Ministry of Health - in six months. In this case, we will achieve the maximum result - both individual and population.

    As far as I understand, only virus-neutralizing antibodies can provide protection. Do tests from commercial laboratories show their level and how accurately?

    Analysis for virus neutralization is available to few top laboratories. But comparative studies were carried out, where they took a test system that shows virus-neutralizing antibodies, and another system that shows antibodies to all parts of the virus. And there was a weak conditional correlation. Therefore, in a sense, quantitative test systems that are calibrated against test systems that show virus-neutralizing antibodies reflect the real essence. Though not 100%. But determining the amount of antibodies is an empty exercise in terms of making a decision about vaccination.

    The level of herd immunity in Russia is now over 60%. A year ago, it was about the need to reach 50% to end the pandemic. Now we are talking about 80% and even about 90%. Is it still worth focusing on herd immunity? Is it achievable at all?

    This is a very important concept: the overall epidemic situation depends on what percentage of the population are those who have immunity, are less at risk of getting sick and transmitting the virus. Today it is clear that 60% is no longer enough. Some countries have already reached 80% coverage, but the incidence rate is not decreasing, sometimes even increasing, but it is important to note that their mortality and the number of severe cases are clearly decreasing. What level is considered the one that will protect us or significantly affect the epidemic process? This is definitely above 80%, but ideally the higher the better.

    From Interview with Chief freelance infectious disease specialist of the Ministry of Health Vladimir Chulanov

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  • ...and if the Harvard study is correct, VAERS data is grossly understated. I think the COVID-19 adverse reactions and deaths are FAR higher. There is either mass formation psychosis OR some nefarious global agenda at work (or both).

  • The former chairman of the Vaccines Taskforce Clive Dix called for an end to mass Covid-19 vaccinations.

    He said: “The Omicron variant is a relatively mild virus. And to just keep vaccinating people and thinking of doing it again to protect the population is, in my view, now a waste of time.”

    He argued instead for a “highly-focused approach” to vaccinate vulnerable people.

    Dix said that even when the booster campaign was announced, he was “critical” of boosting everybody as he is not convinced “it was needed or is needed” for younger people.

    “I think the thinking of the time was very much to stop infection and transmission where clearly these vaccines don’t do that,” he added.

    “We’ve seen that because we’ve seen these huge, huge levels of infection but what [boosters] do – and it’s absolutely clear – they stop people getting seriously ill and dying. 85 per cent of the people who get seriously and dying are the vulnerable and the elderly, so they’re the ones we should focus on.”

    He said the UK government should be “very focused” on how to educate themselves for the “future vaccination programme” next winter, arguing there should be a study to understand the status of the public’s immunity.

    “So, by next winter, we can really have a policy of vaccination that’s educated, using the right vaccines at the right time for the right people.”

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  • Vaccination status in USA.

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  • Health departments in several states confirmed to The Epoch Times that they are looking into a steep surge in the mortality rate for people aged 18 to 49 in 2021 — a majority of which are not linked to COVID-19.

    Deaths among people aged 18 to 49 increased more than 40 percent in the 12 months ending October 2021 compared to the same period in 2018–2019, before the pandemic, according to an analysis by The Epoch Times of death certificate data from the Centers for Disease Control and Prevention (CDC).